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Explaining An Important Genetic Cardiovascular Risk Factor Wed, 08 Sep 2010
New findings reported in the September issue of Cell Metabolism, a Cell Press publication, appear to explain why people who carry specific and common versions of a single gene are more likely to have high cholesterol and to suffer a heart attack. Studies in mice show that the gene, known as sortilin (SORT1), controls the release of LDL (a.k.a...
AHRQ Releases New Spanish Language Guides For Patients Wed, 08 Sep 2010
HHS' Agency for Healthcare Research and Quality today released a series of free evidence-based guides designed to help Spanish speakers understand and compare the risks, benefits and side effects of treatments for eight health conditions. The guides provide valuable information that patients can use in talking with their clinicians...
Non-stick Cookware And Waterproof Fabrics Linked To Higher Cholesterol Levels In Kids Tue, 07 Sep 2010
Chemicals used in the production of non-stick cookware and waterproof fabrics, known as perfluoroalkyl acids, can get into children's blood and raise their LDL cholesterol levels ("bad cholesterol" levels), says an article published in Archives of Pediatrics & Adolescent Medicine. Examples of perfluoroalkyl acids include PFOA (perfluorooctanoic acid) and PFOS (perfluorooctanesulfonate)...
Data From Mipomersen Phase 3 Trial In heFH Patients Presented At ESC Wed, 01 Sep 2010
Genzyme Corp. (NASDAQ: GENZ) and Isis Pharmaceuticals Inc. (NASDAQ: ISIS) announced that data from the phase 3 study of mipomersen in patients with heterozygous familial hypercholesterolemia (heFH) were presented at the European Society of Cardiology's Congress 2010 in Stockholm, Sweden...
Netherlands Study Shows Need For Dose Management Care When Switching To Generic Statins Wed, 01 Sep 2010
Research conducted in the Netherlands has highlighted the need for care when switching patients under treatment for high cholesterol from branded to generic drug families. The study shows that much of the switching can result in patients inadvertently receiving non-equivalent doses, potentially leading to an increased risk of downstream heart disease and stroke...
Grapefruit's Bitter Taste Holds A Sweet Promise For Diabetes Therapy Fri, 27 Aug 2010
Naringenin, an antioxidant derived from the bitter flavor of grapefruits and other citrus fruits, may cause the liver to break down fat while increasing insulin sensitivity, a process that naturally occurs during long periods of fasting...
Expanded Lipoprotein Testing, VAP® Cholesterol Test Discussed At National Lipid Association Summer Clinical Lipid Update Thu, 26 Aug 2010
Atherotech Diagnostics Lab will exhibit its VAP® Cholesterol Test in booth 105 at the National Lipid Association (NLA) Summer 2010 Clinical Lipid Update. The meeting takes place August 27-29 at the Mayflower Hotel in Washington, D.C...
Impax Laboratories Confirms Patent Challenge Relating To VYTORIN(R), 10 Mg/80 Mg Mon, 23 Aug 2010
Impax Laboratories, Inc. (NASDAQ: IPXL) today confirms that it has initiated a challenge of patents listed by MSP Singapore Co. LLC in connection with VYTORIN® (ezetimibe/simvastatin), 10 mg/80 mg. Impax filed its Abbreviated New Drug Application ("ANDA") containing a paragraph IV certification for a generic version of VYTORIN® with the U.S. Food & Drug Administration ("FDA")...
Outlets Should Offer Free Statins With Junk Food Say UK Researchers Fri, 13 Aug 2010
Imagine this: order a cheeseburger and fries, and pick up a free cholesterol-busting statin tablet along with the other free condiments, that's what a group of UK researchers suggests you should be able to do at fast food outlets as a way to offset the increase in heart attack risk from eating junk food...
Amarin's AMR101 Pivotal Phase 3 MARINE Clinical Trial Completes Patient Enrollment And Randomization Wed, 11 Aug 2010
Amarin Corporation plc (Nasdaq: AMRN), a clinical-stage biopharmaceutical company with a focus on cardiovascular disease, announced that its MARINE trial, a Phase 3 clinical trial of AMR101, has completed patient enrollment and randomization into the treatment phase of this trial...
Abbott's SIMCOR® (Niacin Extended-Release / Simvastatin) Receives FDA Approval For New Dosage Strengths Fri, 06 Aug 2010
Abbott has received U.S. Food and Drug Administration (FDA) approval for two new dosage strengths of SIMCOR®, a cholesterol medication. The new SIMCOR dosage strengths combine 40 mg of simvastatin - the most commonly prescribed dose of simvastatin - with either 500 mg or 1,000 mg of niacin extended-release...
Disrupting Body Clock Could Keep Triglycerides High, Raising Risk Of Heart Disease Thu, 05 Aug 2010
From studies on mice, researchers in the US have discovered that disrupting the body clock or circadian rhythm could interfere with a normal 24 hour cycle of high and low triglycerides in a way that leaves them at a high level all the time, potentially raising the risk of atherosclerosis and heart disease. You can read how Dr M...
95 Genetic Variants Associated With Cholesterol, Triglycerides, Identified By Scientists Thu, 05 Aug 2010
A global team of researchers co-led by the University of Michigan School of Public Health has discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk...
Genome Scanning Finds Genes For Cholesterol And Heart Disease That Could Be Important Targets For Treatment Thu, 05 Aug 2010
Two international studies published in a leading journal this week have pinpointed genes for cholesterol and heart disease that could be important targets for treatment, and demonstrate the potential clinical value of "genome scanning" or GWAS, genome wide association studies, in developing new diagnostic tests and therapies for diseases with genetic risks...
Low Carb Diet Better For Cardiovascular Health Than Low Fat Diet Tue, 03 Aug 2010
Researchers from of the Center for Obesity Research and Education at Temple University, Philadelphia have revealed that after a two-year comparison, a low-carb diet fares about as well as a low-fat diet with regards to weight loss, but low-carb improves cardiovascular risk factors more...
Modestly High Cholesterol Levels In Young People Can Cause Heart Disease Signs By Age 45 Tue, 03 Aug 2010
Relatively young individuals with slightly abnormal cholesterol levels have a real risk of developing signs of heart disease by the time they are 45 years old, according to a new study published in the peer-reviewed medical journal Annals of Internal Medicine. In a 20-year study, researchers gathered data on 3,258 males and females between the ages of 18 and 30 years...
Cholesterol Levels In Young Adults Predict Risk Of Future Heart Disease Tue, 03 Aug 2010
Young people with even modestly elevated cholesterol levels are more likely to develop coronary artery calcium and atherosclerosis later in life, according to a 20-year study released on August 2 by UCSF researchers...
News From Annals Of Internal Medicine: August 3, 2010 Tue, 03 Aug 2010
At Two Years, Low-carb Diet Beats Low-Fat for HDL-Cholesterol Levels Previous studies comparing low-carbohydrate and low-fat diets have not included comprehensive behavioral treatment. Researchers sought to evaluate the long-term effects of a low-carbohydrate versus a low-fat diet when combined with a comprehensive lifestyle modification program...
Disparities In Cardiovascular Risk Based More On Socioeconomic Status Than Race, Ethnicity Tue, 03 Aug 2010
A new UCLA study suggests that disparities in cardiovascular disease risk in the United States are due less to race or ethnicity than to socioeconomic status...
Abbott's SIMCOR(R) (Niacin Extended-Release / Simvastatin) Receives FDA Approval For New Dosage Strengths Thu, 29 Jul 2010
Abbott received U.S. Food and Drug Administration (FDA) approval for two new dosage strengths of SIMCOR®, a cholesterol medication. The new SIMCOR dosage strengths combine 40 mg of simvastatin - the most commonly prescribed dose of simvastatin - with either 500 mg or 1,000 mg of niacin extended-release...
Abbott's SIMCOR ® ( Niacin Extended-release / Simvastatin ) Receives FDA Approval For New Dosage Strengths Thu, 29 Jul 2010
Abbott (NYSE: ABT) received U.S. Food and Drug Administration (FDA) approval for two new dosage strengths of SIMCOR®, a cholesterol medication. The new SIMCOR dosage strengths combine 40 mg of simvastatin the most commonly prescribed dose of simvastatin with either 500 mg or 1,000 mg of niacin extended-release...
Preventing Heart Problems While Keeping A Cool Head Tue, 27 Jul 2010
Max Planck researchers explain the cause of the flushing effect arising from cholesterol treatment with nicotinic acid. Cholesterol influences the health of our hearts and blood vessels. Conventional treatment attempts to reduce the level of "bad" cholesterol, LDL cholesterol, in the blood plasma...
No Firm Conclusions About HDL Cholesterol Can Be Drawn From JUPITER Sub-analysis Sun, 25 Jul 2010
No firm conclusions about HDL cholesterol can be drawn from JUPITER sub-analysis Sophia Antipolis, 23 July 2010: The European Society of Cardiology (ESC) is concerned that interpretations of a paper about cholesterol, published in the Lancet (1), could act to deter ongoing research efforts into developing new therapeutic strategies to increase high density lipoprotein (HDL) cholesterol...
Good Cholesterol Seems Less Important Once Statins Have Lowered Bad Cholesterol Fri, 23 Jul 2010
Results of an international trial suggest that once statins have lowered LDL or "bad" cholesterol, the level of HDL or "good" cholesterol is less important in terms of predicting cardiovascular risk than it is during pre-treatment assessment...
New Links Between Cholesterol And Depression In The Elderly Thu, 22 Jul 2010
Most people know that high cholesterol levels place them at increased risk for heart disease and stroke. Prior research has shown that particular types of strokes contribute to one's risk for depression, and that abnormal blood lipid levels can increase the risk of depression in the elderly...
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