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TPP Global Development Ltd Enters Into An Agreement With The University Of Edinburgh For Future Drug Development Wed, 08 Sep 2010
TPP Global Development Ltd (TPP) announced an agreement with the University of Edinburgh to collaborate on the development of novel pre-clinical intellectual property originated within the University. TPP and the University of Edinburgh will focus on commercialisation opportunities in the areas of nervous system disorders, immunology/inflammation and oncology...
Yeast Holds Clues To Parkinson's Disease Wed, 08 Sep 2010
Yeast could be a powerful ally in the discovery of new therapeutic drugs to treat Parkinson's disease says a scientist presenting his work at the Society for General Microbiology's autumn meeting in Nottingham today...
Roche And ReMYND Enter Into A Strategic Alliance To Develop First-In-Class Disease-Modifying Treatments For Parkinson's And Alzheimer's Disease Tue, 07 Sep 2010
Roche (SIX: RO, ROG; OTCQX: RHHBY) and reMYND announced that they have entered into an agreement to develop novel therapeutics that could slow down neurodegeneration in Parkinson's and Alzheimer's patients by inhibiting α-synuclein and tau toxicity...
Cognitive Impairment In People With Parkinson's Disease Exposed By Study Mon, 06 Sep 2010
Queen's researchers have found that people with Parkinson's disease can perform automated tasks better than people without the disease, but have significant difficulty switching from easy to hard tasks. The findings are a step towards understanding the aspects of the illness that affect the brain's ability to function on a cognitive level...
Santhera And Ipsen Enter Into Licensing Agreement For Fipamezole For The Treatment Of Dyskinesia In Parkinson's Disease Sun, 05 Sep 2010
Santhera Pharmaceuticals (SIX: SANN) and Ipsen (Paris:IPN) (Euronext: IPN; ADR: IPSEY) announced a license agreement for the development and commercialization of fipamezole (antagonist of the adrenergic alpha-2 receptor) for territories outside of North America and Japan...
New Light On The Mechanism Of Parkinson's Disease Thu, 02 Sep 2010
A significant number of Parkinson's disease patients have a mutation of the enzyme Leucine-Rich Repeat Protein Kinase 2 (LRRK2, also known as dardarin). However, little is understood about how it is regulated or functions...
New Parkinson's Gene Is Linked To Immune System Sat, 28 Aug 2010
A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development...
Impax Pharmaceuticals Completes Enrollment In ADVANCE-PD Phase III Trial Of IPX066 In Parkinson's Disease Fri, 27 Aug 2010
Impax Pharmaceuticals, the brand products division of Impax Laboratories, Inc. (NASDAQ: IPXL), announced that it has completed enrollment of its ADVANCE-PD trial. ADVANCE-PD is a multinational Phase III trial of its late-stage product IPX066 in advanced Parkinson's disease (PD) patients with motor fluctuations...
Lipid Peroxides, More Sophisticated Than Their Reputation Wed, 25 Aug 2010
Accumulation of lipid peroxides in the cell are associated with diseases and cellular stress. In the current issue of PNAS researchers at Helmholtz Zentrum München and the Swedish medical university Karolinska Institutet show that lipid peroxides also play an important, yet-unrecognized role in the regulation of receptor tyrosine kinases...
Alnylam And Collaborators Publish New Pre-Clinical Research On Therapeutic Silencing Of Parkinson's Disease Gene Wed, 25 Aug 2010
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, and collaborators at The Parkinson's Institute and the Mayo Clinic have published new research findings in the journal Public Library of Science (PLoS)...
A Promising Target For Developing Treatments Against Parkinson's Disease Tue, 24 Aug 2010
Researchers at Johns Hopkins have shown that using specific drugs can protect nerve cells in mice from the lethal effects of Parkinson's disease. The researchers' findings are published in the August 22 issue of Nature Medicine. The newly discovered drugs block a protein that, when altered in people, leads to Parkinson's disease...
A Promising Target For Developing Treatments Against Parkinson's Disease Tue, 24 Aug 2010
Researchers at Johns Hopkins have shown that using specific drugs can protect nerve cells in mice from the lethal effects of Parkinson's disease. The researchers' findings are published in the August 22 issue of Nature Medicine. The newly discovered drugs block a protein that, when altered in people, leads to Parkinson's disease...
Brain Connections Break Down As We Age Fri, 20 Aug 2010
It's unavoidable: breakdowns in brain connections slow down our physical response times as we age, a new study suggests...
Human Induced Pluripotent Stem Cells Successfully Used To Treat Parkinson's In Rodents Wed, 18 Aug 2010
Researchers at the Buck Institute for Age Research have successfully used human induced pluripotent stem cells (iPSCs) to treat rodents afflicted with Parkinson's Disease (PD)...
Genetic Link Discovered Between Immune System, Parkinson's Disease Mon, 16 Aug 2010
A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics...
Immune System Genes Linked To Parkinson's Disease Mon, 16 Aug 2010
An international team of researchers conducting a genome-wide association study (GWAS) has discovered that common variants in immune system genes are linked to Parkinson's disease...
Development Of Neurochip Technology Will Further Brain Research Of Alzheimer's, Parkinson's Thu, 12 Aug 2010
The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip - or the brain on a microchip - have been involved in the development of new technology that monitors brain cell activity at a resolution never achieved before...
TEMPO Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson's Disease Patients Mon, 09 Aug 2010
H. Lundbeck A/S (Lundbeck) and Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension...
Expectations May Affect Placebo Response In Patients With Parkinson's Disease Sun, 08 Aug 2010
Individuals with Parkinson's disease were more likely to have a neurochemical response to a placebo medication if they were told they had higher odds of receiving an active drug, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals...
TEMPO Extentension Study Further Demonstrates The Benefits Of Azilect® In Early Parkinson's Disease Patients Fri, 06 Aug 2010
Teva Pharmaceutical Industries Ltd. and H. Lundbeck A/S have announced newly published long-term data on Azilect® (rasagiline tablets) from the TEMPO study and its open-label extension. The findings confirm the long-term efficacy, safety and tolerability of Azilect® in patients with Parkinson's disease (PD) and further demonstrate the benefits obtained with early treatment initiation...
New Pathway To Parkinson's And Alzheimer's Diseases Fri, 30 Jul 2010
Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells...
Study Identifies Molecular Mechanism Triggering Parkinson's Disease Fri, 30 Jul 2010
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady...
REM Sleep Disorder Could Be Early Warning Of Parkinson's, Dementia That Develops Decades Later Thu, 29 Jul 2010
American neurologists and sleep experts suggest in a recent study that rapid eye movement (REM) sleep behavior disorder could be an early sign of Parkinson's disease or dementia that develops up to 50 years later. You can read how neurologist and sleep specialist Dr Bradley F...
Envoy To Seek New Parkinson's Disease Therapy With Scripps Thu, 29 Jul 2010
Envoy Therapeutics Inc., a recently formed drug discovery company, announced that it has begun a research collaboration with The Scripps Research Institute to identify new drugs for Parkinson's disease (PD) that have greater efficacy and safety compared to current therapies...
Helping Neurons Fix Themselves In Parkinson's Patients Mon, 26 Jul 2010
A Michigan State University researcher is working to uncover how a protein known as parkin may help nerve cells fight off damage from Parkinson's disease, a strategy that could lead to new therapies for the degenerative ailment...
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