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Novartis And Collaborators Discover Novel Antimalarial Drug Candidate Tue, 07 Sep 2010
Novartis announced that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria...
Researchers Identify Protein That Fights West Nile Virus Mon, 06 Sep 2010
Yale and McGill University scientists have identified a protein that is critical in fighting mosquito-borne West Nile Virus in mice. This finding could have therapeutic implications for controlling the potentially deadly virus in humans. The study appears in the Advance Online Publication of Nature Immunology...
Single-Dose Of Experimental Malaria Drug Clears Parasites In Mice, Represents Potential New Class Of Drugs To Treat Malaria In Humans Mon, 06 Sep 2010
An experimental malaria drug was shown to effectively treat the disease in mice with only a single dose, according to a study published Thursday in the journal Science, Reuters reports (Kelland, 9/2). The new drug, known as NITD609, "represents an entirely new class of medicines to treat malaria ...
IMF, World Bank Announce Increased Aid Measures For Flood Relief In Pakistan Mon, 06 Sep 2010
"The IMF and the World Bank have stepped up aid to flood-hit Pakistan to help the country cope with its worst-ever humanitarian disaster," Agence France-Presse reports...
Antimalarial Drug Diversion Study In Research And Reports In Tropical Medicine Sun, 05 Sep 2010
Study of antimalarial drug diversion published in Research and Reports in Tropical Medicine Background: Antimalarial medicine diversion has been seen across numerous African markets and can lead to serious stock-outs in the public sector, which can be dangerous to countries with high burdens of disease...
Compound Cleared Malaria Parasites Quickly In Mice Sat, 04 Sep 2010
A chemical that rid mice of malaria-causing parasites after a single oral dose may eventually become a new malaria drug if further tests in animals and people uphold the promise of early findings. The compound, NITD609, was developed by an international team of researchers including Elizabeth A. Winzeler, Ph.D...
Opinions: Pakistan's Rebuilding; Kenya's Constitution; Development Financing; Africa's Black Market For Malaria Drugs Fri, 03 Sep 2010
U.S., Other Countries Must Develop Strategy To Ensure Honest, Transparent Pakistani Rebuilding A Washington Post editorial encouraging the U.S. to generously support Pakistan as it recovers from major flooding, states: the "humanitarian interest is heightened by Pakistan's centrality to America's national security interests...
New Antimalarial Compound Shows Promise For Drug Resistant Malaria Fri, 03 Sep 2010
Scientists are developing a new antimalarial drug with a novel mechanism of action which shows promise for clearing a Plasmodium (malaria parasite) infection after a single dose, according to an article published in the journal Science...
Technique That Could Resolve The Problem Of Fake Medicines In Developing Countries Fri, 03 Sep 2010
Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. Researchers from Lund and the UK have now developed a technique that could resolve the situation. In two years the researchers hope to have a prototype ready...
News From The Journal Of Clinical Investigation: Sept. 1, 2010 Fri, 03 Sep 2010
INFECTIOUS DISEASE: Modified adenovirus malaria vaccine works a treat in mice Malaria kills more than 1 million individuals each year. Despite intensive research, there is still no malaria vaccine approved for use. A team of researchers, led by Moriya Tsuji, at the Aaron Diamond AIDS Research Center, New York, has now designed a new vaccine that provides protection from malaria in mice...
Report Finds Some Donated Malaria Drugs Are Being Stolen, Resold In Africa Thu, 02 Sep 2010
Some of the malaria drugs given to Africa by international donors are "being stolen and resold on commercial markets," according to a study to be released Thursday in the journal Research and Reports in Tropical Medicine, the Associated Press reports...
Also In Global Health News: Monkeypox In Congo; Indonesian Volcano; Latrines In Cambodia; Maternal Health In India Wed, 01 Sep 2010
Monkeypox Prevalence Surges In Smallpox 'Vaccine Naive' In Congo The New York Times reports on monkeypox cases, which are "surging in tropical Africa...
Innovative Low Cost, High-Speed Filter Uses Electrified Nanostructures To Purify Water Wed, 01 Sep 2010
By dipping plain cotton cloth in a high-tech broth full of silver nanowires and carbon nanotubes, Stanford researchers have developed a new high-speed, low-cost filter that could easily be implemented to purify water in the developing world. Instead of physically trapping bacteria as most existing filters do, the new filter lets them flow on through with the water...
Several Different Kinds Of Odor Sensors Used By Mosquitoes To Track Human Prey Wed, 01 Sep 2010
It now appears that the malaria mosquito relies on a battery of different types of odor sensors to mediate its most critical behaviors, including how to choose and locate their blood-meal hosts...
Epic Mosquito Season And Re-Emergence Of Dengue Fever In Florida Are Potent Reminders To Stay Protected From Mosquitoes With Insect Shield Tue, 31 Aug 2010
The wet spring followed by hot, summer weather throughout the US has resulted in an explosion of mosquitoes throughout the country. In addition, a recent outbreak of Dengue fever in Florida has heightened awareness about the dangers of insect bites and insect-borne disease. Dengue re-emerged in the United States in 2009 in Key West for the first time since 1934...
How Disease-Causing Parasite Gets Around Human Innate Immunity Tue, 31 Aug 2010
Trypanosomes are parasites responsible for many human and animal diseases, primarily in tropical climates. One disease these parasites cause, African sleeping sickness, results from the bite of infected tsetse flies, putting over 60 million Africans at risk in 36 sub-Saharan countries...
Also In Global Health News: GM Mosquitoes; Iodine Deficiency In Nepal; South African Health Workers Strike; Novartis To Build Vaccine Plant In Brazil; Tue, 31 Aug 2010
Malaysia Considers GM Mosquito Release To Control Dengue Fever Malaysia is still "considering releasing" up to 3,000 mosquitoes that are genetically modified to "combat dengue fever, in a landmark field trial that has come in for criticism from environmentalists," Agence France-Presse reports...
Authorities Arrest More Than 80 People, Seize 10 Tons Of Counterfeit Meds In E. Africa Mon, 30 Aug 2010
Authorities have arrested more than 80 people and seized 10 tons of counterfeit medicines across six East African countries, the international police agency Interpol announced Thursday, United Press International reports (8/26). Interpol, together with a WHO unit, "targeted alleged networks of counterfeit drugs makers, traffickers and vendors," the Canadian Press reports (8/26)...
Cameroon Rolls Out Emergency Cholera Plan As Region's Outbreak Continues Mon, 30 Aug 2010
Cameroon will need approximately $4.8 million for its emergency response to the cholera outbreak, which has killed nearly 300 people in the northern part of the country, Agence France-Presse reports. According to AFP, state radio reported yesterday that "the government's response to the outbreak will be rolled out in two phases...
Elsevier And KIT Sign MoU To Provide ScienceDirect And Scopus To 150 Developing Country Researchers Mon, 30 Aug 2010
Elsevier and the Royal Tropical Institute (KIT) in Amsterdam announced on 26th of August the signing of a Memorandum of Understanding (MoU) providing 150 researchers working in least-developed and low-income countries (for example Benin, Mozambique, Ethiopia, Togo etc...
Determining Genetic Structure Of First Animal To Show Evolutionary Response To Climate Change Sat, 28 Aug 2010
Scientists at the University of Oregon have determined the fine-scale genetic structure of the first animal to show an evolutionary response to rapid climate change. They used a high-throughput sequencing technique called Restriction-site Associated DNA (RAD) tagging to make the discovery...
Popular Insect Repellents Pack A Powerful '1-2' Punch Sat, 28 Aug 2010
Two new studies reveal that the commonly used insect repellents DEET and citronellal each work through a dual stimulation of insect sensory systems. The research findings, published by Cell Pres in the journals Neuron and Current Biology, enhance our understanding of how insects respond to repellents and may lead to the discovery of improved compounds for controlling insect-borne disease...
Keystone Symposia To Hold Conference In Seattle On Immunological Mechanisms Of Vaccination Thu, 26 Aug 2010
Keystone Symposia on Molecular and Cellular Biology will convene its conference on "Immunological Mechanisms of Vaccination" in Seattle, Washington from October 27 to November 1, 2010 at Sheraton Seattle Hotel. This is the first conference of Keystone Symposia's 40th meeting season and its first in Seattle...
World Vision Survey In Pakistan's Hardest-Hit Districts Finds Rapid Increase Of Diarrhea, Skin Diseases In Children Wed, 25 Aug 2010
World Vision says assessments conducted over the last few days near the towns of Muzaffar Garh and Kot Addo in Punjab paint a bleak picture of the impact of the flooding. The Christian humanitarian organization says its reports from Sukkur in the Sindh Province are equally dire...
Primates Protected From Lethal Ebola And Marburg Viruses By Novel 'Antisense' Therapies Wed, 25 Aug 2010
New studies show that treatments targeting specific viral genes protected monkeys infected with deadly Ebola or Marburg viruses. Furthermore, the animals were protected even when therapeutics were administered one hour after exposure - suggesting the approach holds promise for treating accidental infections in laboratory or hospital settings...
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